San Francisco 49ers vs Seattle Seahawks
NFL · Sun, Oct 11, 4:25 PM EDT
Original pick
San Francisco 49ersMoneyline+170on DraftKings
Confidence at pick time: 99/99 (Slight Value)
Factors at pick time
+
Strong Record
2-1 overall (67% win rate)
+
Strong Road Team
2-0 on the road (100%)
+
Scoring Efficiency
Outscoring opponents by 24.0 PPG on the season
+
Record Advantage
Significantly better record than Seattle Seahawks (67% vs 0%)
-
Key Players Out
2 starters impacted: Mykel Williams (DE), Isaac Guerendo (RB)
+
Opponent Injuries
Seattle Seahawks without Zach Charbonnet (RB), Terrion Arnold (CB)
+
Off Bye
45 days of rest coming off a bye
Frequently asked
What was SlateSense's pick for San Francisco 49ers vs Seattle Seahawks?
SlateSense picked San Francisco 49ers Moneyline at +170 with a confidence of 99/99.
When does San Francisco 49ers vs Seattle Seahawks start?
San Francisco 49ers vs Seattle Seahawks is scheduled for Sunday, October 11, 2026 (NFL). Times listed are ET.
How does SlateSense generate its picks?
SlateSense scores each side of every game across 50+ factors including team records, recent form, pitcher/goalie matchups, line movement, weather, injuries, rest, advanced metrics (run differential, net rating, etc.), and market disagreement. The model picks the side with the larger factor score when the gap is meaningful.
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