San Francisco 49ers vs Seattle Seahawks

NFL · Sun, Oct 11, 4:25 PM EDT

AI Pick
Seattle SeahawksMoneyline-205on DraftKings
Confidence 77/99 (Moderate)Market prob 64.5%
Why this pick

Seattle Seahawks have 6 factors working in their favor: 14-3 overall (82% win rate). 6-2 at home (75%). Outscoring opponents by 191.0 PPG on the season. A -3.5-point spread suggests a comfortable win.

Factors driving the pick
+
Strong Record
14-3 overall (82% win rate)
+
Home Dominance
6-2 at home (75%)
+
Scoring Efficiency
Outscoring opponents by 191.0 PPG on the season
+
Winning Streak
On a 7-game winning streak
+
Opponent Injuries
San Francisco 49ers without Brandon Aiyuk (WR)
+
Home Field
Playing at home — crowd, routine, and familiarity advantage
Best lines available
-205
DraftKings
-220
Caesars

Frequently asked

What is SlateSense's pick for San Francisco 49ers vs Seattle Seahawks?

SlateSense's AI model picks Seattle Seahawks Moneyline at -205 on DraftKings, with a confidence of 77/99 (Moderate).

When does San Francisco 49ers vs Seattle Seahawks start?

San Francisco 49ers vs Seattle Seahawks is scheduled for Sunday, October 11, 2026 (NFL). Times listed are ET.

What are the best odds for Seattle Seahawks Moneyline?

Best available: DraftKings (-205), Caesars (-220).

How does SlateSense generate its picks?

SlateSense scores each side of every game across 50+ factors including team records, recent form, pitcher/goalie matchups, line movement, weather, injuries, rest, advanced metrics (run differential, net rating, etc.), and market disagreement. The model picks the side with the larger factor score when the gap is meaningful.

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